Effects of deltamethrin on lipid peroxidation in mice

Yarsan E., Bilgili A., Kanbur M. , Celik S.

VETERINARY AND HUMAN TOXICOLOGY, cilt.44, ss.73-75, 2002 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 44 Konu: 2
  • Basım Tarihi: 2002
  • Dergi Adı: VETERINARY AND HUMAN TOXICOLOGY
  • Sayfa Sayısı: ss.73-75

Özet

Effects of deltamethrin on lipid peroxidation were investigated for subacute. subchronic and chronic periods. Deltamethrin was given to Swiss Albino mice at 1.5, 2.5, or 7.5 mg/kg. Lipid peroxidation was evaluated by determining malondialdehyde (MDA) levels in plasma, and determining glutathione peroxidase (GSH-Px), superoxide dismutase (Cu-Zn SOD) and catalase activities in erythrocytes on days 15, 45, and 60. MDA levels increased in deltamethrin dosed groups, especially for the subchronic and chronic periods. GSH-Px, Cu-Zn SOD and catalase activities in erythrocytes were decreased at high doses of deltamethrin, especially at the high dose (7.5 mg/kg) deltamethrin group.