Variable clinical presentation in primary lymphoedema: report of two cases

Ozyurt A., Sevinc E., BAYKAN A., ARSLAN D., Argun M., PAMUKÇU Ö., ...More

CLINICAL DYSMORPHOLOGY, vol.23, no.3, pp.83-87, 2014 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 23 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.1097/mcd.0000000000000036
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.83-87
  • Keywords: ascites, Hennekam syndrome, octreotide, primary lymphoedema, HENNEKAM-SYNDROME, MENTAL-RETARDATION, LYMPHANGIECTASIA
  • Erciyes University Affiliated: Yes


Lymphoedema is a condition of localized fluid retention and tissue swelling caused by a compromised lymphatic system. Lymphoedema may be primary or secondary and can be inherited. Primary lymphoedema (primary lymphatic dysplasia) is a chronic oedema caused by a developmental abnormality of the lymphatic system. Primary lymphoedema most commonly affects the lower limbs, but other body parts can also be affected. It can be associated with some specific syndromes (i.e. Hennekam syndrome) and genetic disorders. In this article, we report on two patients with congenital multisegmental lymphoedema and Hennekam syndrome, both primary lymphoedemas. (C) 2014 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.