Objective: This randomized-controlled experimental study was conducted to determine the effects of psychoeducation in the clinic and regular telepsychiatric follow-up (via telephone) after discharge on social functioning, drug adherence of patients with schziophrenia. Methods: This study was performed on totally 62 patients, assigned to experiment (n=32) and control (n=30) groups, from 1st July 2010 to 31st May 2011, being followed in Mental Health Center of Kayseri Training and Research Hospital and meeting research criteria. Patients' characteristics were recorded by a form. For the patients in experiment and control groups; before education, after education and after 6-months telephone follow-up Scales of Medication Adherence Rating, Social Functioning were applied. In the psychoeducation process, the patients in the experiment group were given `Manual of Information for Patients with Schziophrenia' prepared by the researcher. After discharge, patients were interviewed by telephone for 6 months, every week regularly in average for 15 minutes. A standard, semi-structured interview form consisting of 7 questions were used for telephone follow-up. Results: For the patients in the experiment group, after physchoeducation and telephone follow-up, the mean scores for adherence to treatment and social functioning scores were increased, the differences between before and after education and after telephone follow-up were significant. Again, the differences between the mean scores of adherence to treatment and social functioning were significant after education and after telephone follow-up for the patients in both experiment and control groups. In addition, the group and time interaction of the mean scores for adherence to treatment and social functioning were significant. Conclusion: According to these results, the psychoeducation and telepsychiatric follow-up via telephone induced increases in adherence to treatment and social functioning for the patients. Supporting the patients with schizophrenia via psychoeducation and telepsychiatric follow-up had positive impact on these patients and these techniques are recommended to be used in patient follow-up at home.