Overlooked prophylaxis of Hepatitis B in patients undergoing hematopoietic stem cell transplantation


Türe Yüce Z. , Kalın Ünüvar G. , Kahveci H. N. , Keklik M. , Ulu Kılıç A.

Erciyes Medical Journal, vol.43, no.1, 2021 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.14744/etd.2020.36786
  • Title of Journal : Erciyes Medical Journal
  • Keywords: Hepatitis B, hematopoietic setem cell transplantation, reverse seroconversion, HBV reactivation, CLINICAL-PRACTICE GUIDELINES, VIRUS REACTIVATION, HEMATOLOGIC MALIGNANCIES, NEGATIVE PATIENTS, RISK-FACTORS, PREVENTION, RECOMMENDATIONS, MANAGEMENT, ANTIBODY, THERAPY

Abstract

Objective: The reactivation rate of dormant hepatitis B virus (HBV) in the liver is between 4.1% and 41.5% in immune-compromised patients. The disappearance of hepatitis B surface antibody (anti-HBs) can be an alarm for hepatitis B reactivation. In this study, the changes in serological status, reactivation rates, and antiviral prophylaxis rates were evaluated.