Characterization of the RNA dependent DNA polymerase of bovine leukemia virus


DEMİRHAN I. , Altanerova V., Chandra A., Gerber T., Hofmann D., Altaner C., ...Daha Fazla

ANTICANCER RESEARCH, cilt.16, ss.2501-2505, 1996 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 16
  • Basım Tarihi: 1996
  • Dergi Adı: ANTICANCER RESEARCH
  • Sayfa Sayıları: ss.2501-2505

Özet

The reverse transcriptase - RNA dependent DNA polymerase of Bovine Leukemia Virus (BLV) was isolated and characterized. The enzyme has a molecular weight of about 80kd and the isoelectric point is 7.6. The enzyme prefers magnesium, as a divalent cation using synthetic homopolymeric template primer poly (C) oligo (dG). Monoclonal antibodies directed against reverse transcriptase of human immunodeficiency virus type I (HIV-I) did not crossreact with the isolated polymerase.