Investigation of Hypothalamus-Pituitary-Gonadal Axis in Epileptic Women Treated for Epilepsy


ERDOĞAN F. F. , Arik Yuksel S. , Ersoy A. Ö. , ÜNLÜHİZARCI K. , TANRIVERDİ F. , KELEŞTİMUR F.

NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, vol.49, no.2, pp.133-138, 2012 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 2
  • Publication Date: 2012
  • Doi Number: 10.4274/npa.y6265
  • Title of Journal : NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY
  • Page Numbers: pp.133-138

Abstract

Objectives: Reproductive endocrine disorders, especially polycystic ovary syndrome (PCOS) are common in epileptic women who are less fertile and suffer from more menstrual and reproductive endocrine disorders than non-epileptic women. The etiology of reproductive endocrine dysfunction in epilepsy has not been determined precisely. The aim of the study was to investigate the hypotalamus-pituitary-gonadal axis, insulin resistance and the prevalence of PCOS in patients with generalized idiopathic or cryptogenic epilepsy and receiving treatment with valproate (VPA) and carbamazepine (CBZ).