Association of TNF-alpha 2308 G > A and ACE I/D gene polymorphisms in hemodialysis patients with arteriovenous fistula thrombosis


ŞENER E. F. , TAHERİ S. , Korkmaz K., ZARARSIZ G. , Serhatlioglu F. , ÜNAL A. , et al.

INTERNATIONAL UROLOGY AND NEPHROLOGY, cilt.46, ss.1419-1425, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 46 Konu: 7
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s11255-013-0580-2
  • Dergi Adı: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Sayfa Sayısı: ss.1419-1425

Özet

Tumor necrosis factor-alpha (TNF - alpha) -308 G > A promoter polymorphism seems to be associated with adverse clinical outcome in hemodialysis patients (HD). Angiotensin-converting enzyme (ACE) gene may be the causative factor contributing to the deterioration of renal functions. The aim of this study was to investigate the relationship between vascular access failure and the genetic polymorphisms of ACE and TNF-alpha gene.