Association of TNF-alpha 2308 G > A and ACE I/D gene polymorphisms in hemodialysis patients with arteriovenous fistula thrombosis

ŞENER E. F., TAHERİ S., Korkmaz K., ZARARSIZ G., Serhatlioglu F., ÜNAL A., ...Daha Fazla

INTERNATIONAL UROLOGY AND NEPHROLOGY, cilt.46, sa.7, ss.1419-1425, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 7
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s11255-013-0580-2
  • Dergi Adı: INTERNATIONAL UROLOGY AND NEPHROLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1419-1425
  • Anahtar Kelimeler: Arteriovenous fistula, Cytokine, Hemodialysis, Polymorphism, Thrombosis, ANGIOTENSIN-CONVERTING ENZYME, STAGE RENAL-DISEASE, VASCULAR ACCESS, SYSTEM, RISK, INFLAMMATION, DIALYSIS, PROMOTER, FAILURE
  • Erciyes Üniversitesi Adresli: Evet

Özet

Tumor necrosis factor-alpha (TNF - alpha) -308 G > A promoter polymorphism seems to be associated with adverse clinical outcome in hemodialysis patients (HD). Angiotensin-converting enzyme (ACE) gene may be the causative factor contributing to the deterioration of renal functions. The aim of this study was to investigate the relationship between vascular access failure and the genetic polymorphisms of ACE and TNF-alpha gene.