Prevalence and genotypes of hepatitis G virus among hemodialysis patients in Eastern Anatolia, Turkey


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ÖZDARENDELİ A. , Toroman Z., Kalkan A., Kilic S., Ozden M., DOYMAZ M. Z.

MEDICAL PRINCIPLES AND PRACTICE, vol.14, no.2, pp.102-106, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 2
  • Publication Date: 2005
  • Doi Number: 10.1159/000083920
  • Title of Journal : MEDICAL PRINCIPLES AND PRACTICE
  • Page Numbers: pp.102-106
  • Keywords: hepatitis G virus, hemodialysis patients, genotypes, East Anatolia, Turkey, CLINICAL-SIGNIFICANCE, HGV INFECTION, EPIDEMIOLOGY, RNA, DISEASE, LIVER, SERUM

Abstract

Objectives: To study the prevalence and genotype distribution of hepatitis G virus (HGV) in hemodialysis patients in East Anatolia, Turkey. Subjects and Materials: Eighty-nine hemodialysis patients and 30 healthy individuals were analyzed by using reverse-transcriptase nested polymerase chain reaction with primers specific for 5' untranslated region. HGV genotyping was performed by PCR and three randomly selected HGV-positive samples were sequenced. Results: Of the 89 hemodialysis patients, HGV RNA was detected in 9 (10.2%). All of our isolates were assigned to genotype 2. Conclusion: Our results showed that hemodialysis patients carry the risk for HGV infection in East Anatolia, Turkey. Copyright (C) 2005 S. Karger AG, Basel.