The protective effects of grape seed extract on MDA, AOPP, apoptosis and eNOS expression in testicular torsion: an experimental study

BAYATLI F., AKKUŞ D., KILIÇ E., SARAYMEN R., Sonmez M. F.

WORLD JOURNAL OF UROLOGY, vol.31, no.3, pp.615-622, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.1007/s00345-013-1049-8
  • Journal Name: WORLD JOURNAL OF UROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.615-622
  • Keywords: Testicular torsion, Grape seed proanthocyanidin extract, Apoptosis, eNOS, Rat, ISCHEMIA-REPERFUSION INJURY, NITRIC-OXIDE SYNTHASE, OXIDATIVE STRESS, DELAYED PHASE, BLOOD-FLOW, RAT TESTIS, TORSION/DETORSION, SPERMATOGENESIS
  • Erciyes University Affiliated: Yes

Abstract

Grape seed proanthocyanidin extract (GSPE) is a potent antioxidant and a free radical scavenger. This study was designed to determine whether GSPE could protect against dysfunction and oxidative stress induced by torsion-detorsion injury in rat testis.