Crystal structure and Hirshfeld surface analysis of 2,2,2-trifluoro-1-(7-methylumidazo[l ,2-a]pyridin-3-yl)ethan-1-one
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, vol.78, pp.12-21, 2022 (ESCI, Scopus)
- Publication Type: Article / Article
- Volume: 78
- Publication Date: 2022
- Doi Number: 10.1107/s2056989021012676
- Journal Name: ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS
- Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus
- Page Numbers: pp.12-21
- Keywords: crystal structure, imidazo[1,2-a]pyridine, hydrogen bonds, F center dot center dot center dot F contacts, Hirshfeld surface analysis
- Open Archive Collection: AVESIS Open Access Collection
- Erciyes University Affiliated: Yes
Abstract
The bicyclic imidazo[1,2-a]pyridine core in the molecule of the title compound, C10H7F3N2O, is planar within 0.004 (1) angstrom. In the crystal, the molecules are linked by pairs of C-H center dot center dot center dot N and C-H center dot center dot center dot O hydrogen bonds, forming strips. These strips are connected by the F center dot center dot center dot F contacts into layers, which are further joined by pi-pi stacking interactions. The Hirshfeld surface analysis and fingerprint plots reveal that molecular packing is governed by F center dot center dot center dot H/H center dot center dot center dot F (31.6%), H center dot center dot center dot H (16.8%), C center dot center dot center dot H/H center dot center dot center dot C (13.8%) and O center dot center dot center dot H/H center dot center dot center dot O (8.5%) contacts.