Combined branched-DNA and conventional HBV PCR assays for detection of serum HBV-DNA in hepatitis B e antigen-positive chronic hepatitis B patients

ÖZDARENDELİ A., Toroman Z., Bulut Y., Demirbag K., Kalkan A., Ozden M., ...More

HEPATO-GASTROENTEROLOGY, vol.53, no.67, pp.106-109, 2006 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 53 Issue: 67
  • Publication Date: 2006
  • Journal Name: HEPATO-GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.106-109
  • Keywords: hepatitis B, patients with HBeAg-positive chronic hepatitis B, branched DNA assay, HBVPCR, VIRUS-DNA, POLYMERASE, QUANTIFICATION, QUANTITATION
  • Erciyes University Affiliated: No

Abstract

Background/Aims: Monitoring of HBV replication level is very useful for the management of patients with chronic HBV. However, the use of the correct tools to quantify HBV-DNA levels in serum and monitor the replication of HBV is of paramount importance in terms of diagnosis, and antiviral treatment of patients with chronic HBV infection. The aim of this study was to combine the bDNA assay and HBV PCR to improve detection of viremia the patients with HBeAg-positive chronic hepatitis B infection.