Atıf İçin Kopyala
Yavuz S., Sabanci N., SARIPINAR E.
CURRENT COMPUTER-AIDED DRUG DESIGN, cilt.14, sa.1, ss.79-94, 2018 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
14
Sayı:
1
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Basım Tarihi:
2018
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Doi Numarası:
10.2174/1573409913666170529103206
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Dergi Adı:
CURRENT COMPUTER-AIDED DRUG DESIGN
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.79-94
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Anahtar Kelimeler:
4D-QSAR, ruthenium(II) arene complexes, pharmacophore, electron conformational-genetic algorithm method, BIOACTIVITY PREDICTION, CORRELATION-COEFFICIENT, IDENTIFICATION, QSAR, DERIVATIVES, VALIDATION, THIOSEMICARBAZONE, EVALUATE, PROPOSAL, LIGANDS
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Erciyes Üniversitesi Adresli:
Evet
Özet
Objective: The EC-GA method was employed in this study as a 4D-QSAR method, for the identification of the pharmacophore (Pha) of ruthenium(II) arene complex derivatives and quantitative prediction of activity.