Pharmacophore Modelling and 4D-QSAR Study of Ruthenium(II) Arene Complexes as Anticancer Agents (Inhibitors) by Electron Conformational-Genetic Algorithm Method


Yavuz S. , Sabanci N., SARIPINAR E.

CURRENT COMPUTER-AIDED DRUG DESIGN, cilt.14, ss.79-94, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 14 Konu: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2174/1573409913666170529103206
  • Dergi Adı: CURRENT COMPUTER-AIDED DRUG DESIGN
  • Sayfa Sayısı: ss.79-94

Özet

Objective: The EC-GA method was employed in this study as a 4D-QSAR method, for the identification of the pharmacophore (Pha) of ruthenium(II) arene complex derivatives and quantitative prediction of activity.