Effects of pentoxifylline in the prevention of ovarian hyperstimulation syndrome in a rabbit model

Serin I. S. , Özçelik B. , Bekyürek T., Öztürk F. , Koç N., Şahin Y.

GYNECOLOGICAL ENDOCRINOLOGY, cilt.16, ss.355-359, 2002 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 16 Konu: 5
  • Basım Tarihi: 2002
  • Sayfa Sayısı: ss.355-359


Tumor necrosis factor alpha (TNF-alpha) and other cytokines have been implicated in the pathogenesis of ovarian hyperstimulation syndrome (OHSS). Pentoxifylline, a methylxanthine derivative, was found to inhibit TNF-alpha synthesis. The aim of this study was to evaluate whether the use of petoxifylline would prevent the occurrence of OHSS in a rabbit model