Effects of pentoxifylline in the prevention of ovarian hyperstimulation syndrome in a rabbit model

Serin I. S., Özçelik B., Bekyürek T., Öztürk F., Koç N., Şahin Y.

GYNECOLOGICAL ENDOCRINOLOGY, vol.16, no.5, pp.355-359, 2002 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 5
  • Publication Date: 2002
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.355-359
  • Erciyes University Affiliated: Yes


Tumor necrosis factor alpha (TNF-alpha) and other cytokines have been implicated in the pathogenesis of ovarian hyperstimulation syndrome (OHSS). Pentoxifylline, a methylxanthine derivative, was found to inhibit TNF-alpha synthesis. The aim of this study was to evaluate whether the use of petoxifylline would prevent the occurrence of OHSS in a rabbit model