Growth hormone replacement therapy in adults with growth hormone deficiency: Benefits and cost-effectiveness
Expert Review of Pharmacoeconomics and Outcomes Research, vol.6, no.2, pp.131-138, 2006 (Scopus)
- Publication Type: Article / Review
- Volume: 6 Issue: 2
- Publication Date: 2006
- Doi Number: 10.1586/14737167.6.2.131
- Journal Name: Expert Review of Pharmacoeconomics and Outcomes Research
- Journal Indexes: Scopus
- Page Numbers: pp.131-138
- Keywords: Cardiovascular risk factors, Cost-effectiveness, Growth hormone, Growth hormone deficiency, Growth hormone replacement therapy, Lipid profile, Osteoporosis, Quality of life, Recombinant human growth hormone
- Erciyes University Affiliated: Yes
Abstract
In recent years, growth hormone deficiency in adults has been accepted as a clinical entity. Although beneficial effects of growth hormone replacement therapy (GHRT) in adults - including improvements in body composition, lipid profile, quality of life and bone mineral density - have been shown in many studies, there are still controversies and ongoing debates regarding GHRT in adults. It seems that this subject will continue to be a hot topic in the near future. Therefore, the aim of this review is to re-evaluate the current understanding on GHRT in adults in the light of recent data. Additionally, the clinical aspects, risks, benefits and cost-effectiveness of GHRT are summarized. © 2006 Future Drugs Ltd.