Growth hormone replacement therapy in adults with growth hormone deficiency: Benefits and cost-effectiveness

Tanriverdi F., ÜNLÜHİZARCI K., Kelestimur F.

Expert Review of Pharmacoeconomics and Outcomes Research, cilt.6, sa.2, ss.131-138, 2006 (Scopus) identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 6 Sayı: 2
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1586/14737167.6.2.131
  • Dergi Adı: Expert Review of Pharmacoeconomics and Outcomes Research
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.131-138
  • Anahtar Kelimeler: Cardiovascular risk factors, Cost-effectiveness, Growth hormone, Growth hormone deficiency, Growth hormone replacement therapy, Lipid profile, Osteoporosis, Quality of life, Recombinant human growth hormone
  • Erciyes Üniversitesi Adresli: Evet

Özet

In recent years, growth hormone deficiency in adults has been accepted as a clinical entity. Although beneficial effects of growth hormone replacement therapy (GHRT) in adults - including improvements in body composition, lipid profile, quality of life and bone mineral density - have been shown in many studies, there are still controversies and ongoing debates regarding GHRT in adults. It seems that this subject will continue to be a hot topic in the near future. Therefore, the aim of this review is to re-evaluate the current understanding on GHRT in adults in the light of recent data. Additionally, the clinical aspects, risks, benefits and cost-effectiveness of GHRT are summarized. © 2006 Future Drugs Ltd.