Periodontal status in two siblings with severe congenital neutropenia: Diagnosis and mutational analysis of the cases

hakkı s., Aprikyan A., Yildirim S., Aydinbelge M., Gokalp A., Ucar C., ...Daha Fazla

JOURNAL OF PERIODONTOLOGY, cilt.76, sa.5, ss.837-844, 2005 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 76 Sayı: 5
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1902/jop.2005.76.5.837
  • Dergi Adı: JOURNAL OF PERIODONTOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.837-844
  • Erciyes Üniversitesi Adresli: Hayır

Özet

Background: Severe congenital neutropenia (SCN), also known as Kostmann syndrome, was originally reported as an autosomal recessive disease of neutrophil production. The disease is characterized by a maturation arrest of neutrophil precursors at the promyelocytic stage of differentiation and by extremely low levels of mature neutrophils in peripheral blood.