Proton pump inhibitors and mandibular bone quality: A preliminary study

Cosgunarslan A., CANGER E. M., SOYDAN ÇABUK D.

DENTOMAXILLOFACIAL RADIOLOGY, vol.50, no.6, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 6
  • Publication Date: 2021
  • Doi Number: 10.1259/dmfr.20200505
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE
  • Keywords: Proton Pump Inhibitors, Fractals, Mandible, Radiography, Panoramic, Radiography, Dental, DENTAL IMPLANT FAILURE, FRACTAL DIMENSION, RISK, OSTEOPOROSIS, MEDICATIONS, RADIOGRAPHS
  • Erciyes University Affiliated: Yes


Objectives: Proton pump inhibitors (PPI) provide a long-lasting anti-acidic effect by inhibiting the proton pump, and they are one of the most commonly prescribed drugs worldwide. PPIs adversely affect the bone structure via deficiency of vitamins and minerals. The aim of this study was to investigate the possible PPI-induced bone changes in the mandible on panoramic radiographs with the methods of fractal analysis and panoramic morphometric indices.