Higher NORs-expression in lymphocyte of trisomy 21 babies/children: In vivo evaluation

Imamoglu, NEFİSE; Demirtas, H; Donmez-Altuntas, HAMİYET; Ilten, A

doi:10.1016/j.micron.2005.05.002

Higher NORs-expression in lymphocyte of trisomy 21 babies/children: In vivo evaluation

Atıf İçin Kopyala

Imamoglu N. N., Demirtas H., Donmez-Altuntas H., Ilten A.

MICRON, cilt.36, sa.6, ss.503-507, 2005 (SCI-Expanded)

Yayın Türü: Makale / Derleme
Cilt numarası: 36 Sayı: 6
Basım Tarihi: 2005
Doi Numarası: 10.1016/j.micron.2005.05.002
Dergi Adı: MICRON
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.503-507
Anahtar Kelimeler: Down syndrome, trisomy 21, in vivo AgNORs, DOWN-SYNDROME BRAIN, PROTEIN-LEVELS, CHROMOSOME-21, AGNOR, REGIONS
Erciyes Üniversitesi Adresli: Evet

Özet

Extra chromosome 21 of Down syndrome (DS) or trisomy 21 patients contains an average of 40 extra copies of rRNA genes and the in vivo regulation of these genes is not known. The objective of this work is to compare the NORs expression in interphase nuclei in non-stimulated lymphocytes of DS patients and healthy controls.