Analysis of grayanatoxin in Rhododendron honey and effect on antioxidant parameters in rats


Sibel S. , Enis Y. M. , Huseyin S., TIMUCIN A. A. , DURAN O.

JOURNAL OF ETHNOPHARMACOLOGY, vol.156, pp.155-161, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 156
  • Publication Date: 2014
  • Doi Number: 10.1016/j.jep.2014.08.027
  • Title of Journal : JOURNAL OF ETHNOPHARMACOLOGY
  • Page Numbers: pp.155-161
  • Keywords: Rhododendron (mad) Honey, Grayanotoxin, Antioxidant activity, MDA, Rat, MAD-HONEY, INTESTINAL MORPHOLOGY, SODIUM-CHANNEL, GRAYANOTOXIN, ACID, SITE

Abstract

Ethnopharmacological relevance: Rhododendron honey, locally known as "mad honey", contains gryanotoksin (GTX) and thus induces toxic effects when consumed in large amounts. But, it is still popularly used for treating medical conditions such as high blood pressure or gastro-intestinal disorders. The aim of this study was to evaluate the effect of GTX on antioxidant parameters measured from rats fed with Rhododendron honey.