Mesoporous one-component gold microshells as 3d sers substrates

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Vikulina A. S., Stetsyura I. Y., ÖNSES M. S., YILMAZ E., Skirtach A. G., Volodkin D.

Biosensors, cilt.11, sa.10, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 11 Sayı: 10
  • Basım Tarihi: 2021
  • Doi Numarası: 10.3390/bios11100380
  • Dergi Adı: Biosensors
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Applied Science & Technology Source, EMBASE, INSPEC, MEDLINE, Directory of Open Access Journals
  • Anahtar Kelimeler: calcium carbonate, vaterite, hard templating, Raman spectroscopy, microparticles, ENHANCED RAMAN-SPECTROSCOPY, VATERITE CALCIUM-CARBONATE, MICROPARTICLES, NANOPARTICLES, SILVER, CACO3, TIO2
  • Erciyes Üniversitesi Adresli: Evet

Özet

© 2021 by the author. Licensee MDPI, Basel, Switzerland.Surface-enhanced Raman scattering (SERS) is a powerful analytical tool for label-free analysis that has found a broad spectrum of applications in material, chemical, and biomedical sciences. In recent years, a great interest has been witnessed in the rational design of SERS substrates to amplify Raman signals and optionally allow for the selective detection of analytes, which is especially essential and challenging for biomedical applications. In this study, hard templating of noble metals is proposed as a novel approach for the design of one-component tailor-made SERS platforms. Porous Au microparticles were fabricated via dual ex situ adsorption of Au nanoparticles and in situ reduction of HAuCl4 on mesoporous sacrificial microcrystals of vaterite CaCO3. Elimination of the microcrystals at mild conditions resulted in the formation of stable mesoporous one-component Au microshells. SERS performance of the microshells at very low 0.4 µW laser power was probed using rhodamine B and bovine serum albumin showing enhancement factors of 2 × 108 and 8 × 108, respectively. The proposed strategy opens broad avenues for the design and scalable fabrication of one-component porous metal particles that can serve as superior SERS platforms possessing both excellent plasmonic properties and the possibility of selective inclusion of analyte molecules and/or SERS nanotags for highly specific SERS analysis.