Taurine attenuates lung ischemia-reperfusion injury after lung transplantation in rats


Guler L., Tavlasoglu M., Yucel O., Guler A., Sahin M. A. , Kurkluoglu M., ...More

JOURNAL OF ANESTHESIA, vol.28, no.3, pp.347-353, 2014 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 3
  • Publication Date: 2014
  • Doi Number: 10.1007/s00540-013-1741-2
  • Title of Journal : JOURNAL OF ANESTHESIA
  • Page Numbers: pp.347-353
  • Keywords: Lung transplantation, Rat model, Ischemia-reperfusion injury, Taurine, PROTECTS, MODEL

Abstract

Taurine, the major intracellular free amino acid found in high concentrations in mammalian cells, is known to be an endogenous antioxidant and a membrane-stabilizing agent. It was hypothesized that taurine may be effective in reducing ischemia-reperfusion injury after lung transplantation and an experimental study was conducted in a rat model.