Taurine attenuates lung ischemia-reperfusion injury after lung transplantation in rats

Guler L., Tavlasoglu M., Yucel O., Guler A., Sahin M. A., Kurkluoglu M., ...Daha Fazla

JOURNAL OF ANESTHESIA, cilt.28, sa.3, ss.347-353, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 28 Sayı: 3
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1007/s00540-013-1741-2
  • Dergi Adı: JOURNAL OF ANESTHESIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.347-353
  • Anahtar Kelimeler: Lung transplantation, Rat model, Ischemia-reperfusion injury, Taurine, PROTECTS, MODEL
  • Erciyes Üniversitesi Adresli: Evet

Özet

Taurine, the major intracellular free amino acid found in high concentrations in mammalian cells, is known to be an endogenous antioxidant and a membrane-stabilizing agent. It was hypothesized that taurine may be effective in reducing ischemia-reperfusion injury after lung transplantation and an experimental study was conducted in a rat model.