Taurine attenuates lung ischemia-reperfusion injury after lung transplantation in rats

Guler, Leyla; Tavlasoglu, Murat; Yucel, Orhan; Guler, Adem; Sahin, Mehmet; Kurkluoglu, Mustafa; Sirin, Yusuf; Eken, AYŞE; Gamsizkan, Mehmet; Dakak, Mehmet; Gurkok, Sedat; Genc, Onur

doi:10.1007/s00540-013-1741-2

Taurine attenuates lung ischemia-reperfusion injury after lung transplantation in rats

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Guler L., Tavlasoglu M., Yucel O., Guler A., Sahin M. A., Kurkluoglu M., ...More

JOURNAL OF ANESTHESIA, vol.28, no.3, pp.347-353, 2014 (SCI-Expanded)

Publication Type: Article / Article
Volume: 28 Issue: 3
Publication Date: 2014
Doi Number: 10.1007/s00540-013-1741-2
Journal Name: JOURNAL OF ANESTHESIA
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.347-353
Keywords: Lung transplantation, Rat model, Ischemia-reperfusion injury, Taurine
Erciyes University Affiliated: Yes

Abstract

Taurine, the major intracellular free amino acid found in high concentrations in mammalian cells, is known to be an endogenous antioxidant and a membrane-stabilizing agent. It was hypothesized that taurine may be effective in reducing ischemia-reperfusion injury after lung transplantation and an experimental study was conducted in a rat model.