Taurine attenuates lung ischemia-reperfusion injury after lung transplantation in rats
JOURNAL OF ANESTHESIA, vol.28, no.3, pp.347-353, 2014 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 28 Issue: 3
- Publication Date: 2014
- Doi Number: 10.1007/s00540-013-1741-2
- Journal Name: JOURNAL OF ANESTHESIA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Page Numbers: pp.347-353
- Keywords: Lung transplantation, Rat model, Ischemia-reperfusion injury, Taurine
- Erciyes University Affiliated: Yes
Abstract
Taurine, the major intracellular free amino acid found in high concentrations in mammalian cells, is known to be an endogenous antioxidant and a membrane-stabilizing agent. It was hypothesized that taurine may be effective in reducing ischemia-reperfusion injury after lung transplantation and an experimental study was conducted in a rat model.