The association of profilin-1 levels with survival in chronic kidney disease

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EROĞLU E., UNAL H. U., Guclu A., KOÇYİĞİT I., KARAMAN M., SAGLAM M., ...More

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, vol.47, no.12, 2017 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 47 Issue: 12
• Publication Date: 2017
• Doi Number: 10.1111/eci.12839
• Journal Name: EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Erciyes University Affiliated: Yes

Abstract

BackgroundProfilin-1 is a ubiquitous, actin-binding protein that plays an important role in the regulation of actin polymerization and cytoskeleton remodelling and contributes to vascular dysfunction. We conducted this study to investigate the association of serum profilin-1 levels with fatal and nonfatal CVE in a cohort of patients with stage 1-5 CKD.