Akademik Veri Yönetim Sistemi
Journal of Dermatological Treatment, cilt.36, sa.1, 2025 (SCI-Expanded, Scopus)
Objective: Androgenic alopecia (AGA) is a genetic, non-scarring hair loss disorder influenced by peripheral androgens, affecting patients’ appearance, and quality of life. This study compared the effects of 5% minoxidil, platelet-rich plasma (PRP), and their combination on hair count, telogen/anagen ratio, and vellus hair in AGA patients. Material and methods: This retrospective study included AGA patients treated at the dermatology department. Dermoscopic images taken before and 6 months after treatment with the Molemax device were analyzed using Tricoscan software. Demographic data, disease characteristics, and previous treatments were recorded. Staging followed the Ludwig and Hamilton–Norwood classifications. Patients were categorized into three groups: Group I (5% minoxidil), Group II (PRP), and Group III (combined therapy). Results: The study included 45 patients (53.3% female; mean age 27.8 ± 8.6 years). Groups II and III showed significant improvement in hair count, density, terminal hair count, and anagen ratio (p < 0.05). Vellus hair count and density significantly decreased in Group III (p < 0.05). Patient-reported improvement did not differ significantly among groups (p > 0.05). Conclusion: PRP improves hair growth parameters in AGA and is more effective when combined with minoxidil, especially in reducing vellus hair. These results support PRP’s role in AGA treatment.