Crystal structure of ethyl (4R)-2-amino-7-hydroxy-4-phenyl-4H-chromene-3-carboxylate


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Mague J. T. , Mohamed S. K. , AKKURT M. , Younes S. H. H. , Albayati M. R.

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, vol.71, 2015 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 71
  • Publication Date: 2015
  • Doi Number: 10.1107/s2056989015012013
  • Title of Journal : ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS

Abstract

In the title compound, C18H17NO4, the dihedral angle between the phenyl ring and the fused six-membered ring is 77.65 (4)degrees. The conformation of the molecule is determined in part by an intramolecular N-H center dot center dot center dot O hydrogen bond between the amino H atom and the carbonyl O atom, forming an S(6) motif. In the crystal, molecules are linked into N-H center dot center dot center dot O hydrogen-bonded inversion dimers which are then connected into chains along [001], forming a two-dimensional network parallel to (100) via O-H center dot center dot center dot O hydrogen bonds. C-H center dot center dot center dot O interactions further contribute to the crystal stability. The ethyl group is disordered over two sets of sites in a 0.801 (5): 0.199 (5) ratio.