Herbal Ingredients in the Prevention of Breast Cancer: Comprehensive Review of Potential Molecular Targets and Role of Natural Products

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AKKOL E., BARDAKCI H., BARAK T. H., Aschner M., ŞEKER KARATOPRAK G., Khan H., ...Daha Fazla

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, cilt.2022, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Derleme
  • Cilt numarası: 2022
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1155/2022/6044640
  • Dergi Adı: OXIDATIVE MEDICINE AND CELLULAR LONGEVITY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Compendex, EMBASE, MEDLINE, Directory of Open Access Journals
  • Erciyes Üniversitesi Adresli: Evet

Özet

Among various cancers, breast cancer is the most prevalent type in women throughout the world. Breast cancer treatment is challenging due to complex nature of the etiology of disease. Cell division cycle alterations are often encountered in a variety of cancer types including breast cancer. Common treatments include chemotherapy, surgery, radiotherapy, and hormonal therapy; however, adverse effects and multidrug resistance lead to complications and noncompliance. Accordingly, there is an increasing demand for natural products from medicinal plants and foods. This review summarizes molecular mechanisms of signaling pathways in breast cancer and identifies mechanisms by which natural compounds may exert their efficacy in the treatment of breast cancer.