This study was carried out to determine the effects of irrigation levels on yield and quality of paprika pepper under Harran plain conditions of Turkey. Different water stress levels under drip irrigation system were created by applying 125% of cumulative Class-A Pan evaporation (CAP(125)), 100% (CAP(100)), 75% (CAP(75)) and 50% (CAP(50)) of cumulative class-A-pan (CAP) evaporation in every 3 days. Besides, an irrigation treatment with IRSIS (Irrigation Scheduling Information System) computer program was created and applied as an alternative irrigation program. Three paprika pepper cultivars (Ace, King and Queens) were tested. Experiments were conducted in randomized blocks split plots design with 3 replications in 2005 at Koruklu Station of GAP Regional Development Administration located in Harran Plain of Sarliurfa, Turkey. Applied irrigation water amount and ET (Evapotranspiration) values for IRSIS treatment were 874 mm and 908 mm, respectively. Applied irrigation amount and ET values of CAP(125) and CAP(50) were between 254-568 mm and 368-602 mm, respectively. The highest yield was obtained from IRSIS treatment with 25.63 t ha(-1) and the lowest yield was obtained from CAP(50) with 11.72 t ha(-1). The yield was significantly affected by cultivar, irrigation and cultivar x irrigation interactions. The average moisture, ASTA (American Spice Trade Association), capsaicin, vitamin C and beta-carotene contents were respectively varied between 83.96 - 84.76%, between 225.76-286.22 mg kg(-1), between 1404.11-2408.11 mg kg(-1) and between 77.88-113.00 mg kg(-1). Beta-carotene contents were not affected significantly by the cultivars, irrigations and interactions. The effects of irrigation and interactions on vitamin C and capsaicin were not also significant while the effects of cultivar on vitamin C and capsaicin were significant at P<0.05 level. It was observed in this study that sufficient yield levels of paprika peppers might be achieved through implementation of proper irrigation and care practices.