The effects of N-acetylcysteine on cisplatin induced cardiotoxicity

Gunturk, Ee; Yucel, B; Gunturk, İnayet; Yazici, CEVAT; Yay, ARZU; Kose, SEMA

doi:10.4149/bll_2019_068

The effects of N-acetylcysteine on cisplatin induced cardiotoxicity

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Gunturk E., Yucel B., Gunturk İ., Yazici C., Yay A. H., Kose K.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.120, no.6, pp.423-428, 2019 (SCI-Expanded)

Publication Type: Article / Article
Volume: 120 Issue: 6
Publication Date: 2019
Doi Number: 10.4149/bll_2019_068
Journal Name: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.423-428
Erciyes University Affiliated: Yes

Abstract

OBJECTIVES: Recent studies reported that oxidative stress is an important mechanism that contributes to cisplatin induced cardiotoxicity. In the present study, the effects of N-acetylcysteine (NAC), which is an antioxidant, on cisplatin induced cardiotoxicity were investigated in a rat model.