Anti-Toxoplasma gondii antibodies in patients with schizophrenia-preliminary findings in a Turkish sample

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Cetinkaya Z., Yazar S., Gecici O., Namli M. N.

SCHIZOPHRENIA BULLETIN, cilt.33, ss.789-791, 2007 (SCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 33 Konu: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1093/schbul/sbm021
  • Sayfa Sayıları: ss.789-791


Schizophrenia is a serious neuropsychiatric disease of uncertain etiology. We investigated the seropositivity rate for anti-Toxoplasma IgG and IgNI antibodies by enzymelinked immunosorbent assay (ELISA) in patients with schizophrenia to ascertain a possible relationship between Toxoplasma gondii and schizophrenia. We selected 100 patients with schizophrenia, 50 with depressive disorder, and 50 healthy volunteers to investigate the seropositivity rate of anti-Toxoplasma antibodies by ELISA. The seropositivity rate for anti-Toxoplasma IgG antibodies among schizophrenia patients (66%) was significantly higher than among patients with depressive disorder or healthy volunteers (P <.01). Thus, there might be a causal relationship between toxoplasmosis and the etiology of schizophrenia.