A comparative study on normal and obese mice indicates that the secretome of mesenchymal stromal cells is influenced by tissue environment and physiopathological conditions.

Ayaz-Guner S., Alessio N., Acar M., Aprile D., Özcan S., Di B., ...Daha Fazla

Cell communication and signaling : CCS, cilt.18, ss.118, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 18
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1186/s12964-020-00614-w
  • Dergi Adı: Cell communication and signaling : CCS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.118
  • Anahtar Kelimeler: Obesity, Mesenchymal stromal cells, Secretome, FOLLISTATIN-LIKE 3, ADIPOSE-TISSUE, BONE-MARROW, STEM-CELLS, DIFFERENTIATION, EXPRESSION, BETA, PLACENTA
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background: The term mesenchymal stromal cells (MSCs) designates an assorted cell population comprised of stem cells, progenitor cells, fibroblasts, and stromal cells. MSCs contribute to the homeostatic maintenance of many organs through paracrine and long-distance signaling. Tissue environment, in both physiological and pathological conditions, may affect the intercellular communication of MSCs.