The endocrine disruptor bisphenol A may play a role in the aetiopathogenesis of polycystic ovary syndrome in adolescent girls

Akin L., KENDİRCİ M., Narin F., Kurtoglu S., SARAYMEN R., KONDOLOT M., ...Daha Fazla

ACTA PAEDIATRICA, cilt.104, sa.4, 2015 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 104 Sayı: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1111/apa.12885
  • Dergi Adı: ACTA PAEDIATRICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Anahtar Kelimeler: Adolescents, Bisphenol A, Endocrine disruptors, Polycystic ovary syndrome, NEONATAL EXPOSURE, SERUM, PCOS, ANDROGEN
  • Erciyes Üniversitesi Adresli: Evet

Özet

AimExperimental in vitro studies have shown that bisphenol A affects steroidogenesis, folliculogenesis and ovarian morphology. The aim of this study was to investigate the role of the endocrine disruptor bisphenol A in the aetiopathogenesis of polycystic ovary syndrome (PCOS) in adolescents and its relationship with metabolic parameters, insulin resistance and obesity in this population.