The endocrine disruptor bisphenol A may play a role in the aetiopathogenesis of polycystic ovary syndrome in adolescent girls
ACTA PAEDIATRICA, vol.104, no.4, 2015 (SCI-Expanded, Scopus)
- Publication Type: Article / Article
- Volume: 104 Issue: 4
- Publication Date: 2015
- Doi Number: 10.1111/apa.12885
- Journal Name: ACTA PAEDIATRICA
- Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Keywords: Adolescents, Bisphenol A, Endocrine disruptors, Polycystic ovary syndrome, NEONATAL EXPOSURE, SERUM, PCOS, ANDROGEN
- Erciyes University Affiliated: Yes
Abstract
AimExperimental in vitro studies have shown that bisphenol A affects steroidogenesis, folliculogenesis and ovarian morphology. The aim of this study was to investigate the role of the endocrine disruptor bisphenol A in the aetiopathogenesis of polycystic ovary syndrome (PCOS) in adolescents and its relationship with metabolic parameters, insulin resistance and obesity in this population.