Tubular calcium, magnesium, and phosphate excretion during therapeutic hypothermia for neonatal hypoxic-ischemic encephalopathy: A prospective study

Bastug O., Inan D. B., Ozdemir A., Celik B., Bastug F., Karakukcu Ç.

ARCHIVES DE PEDIATRIE, vol.28, no.8, pp.647-651, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 8
  • Publication Date: 2021
  • Doi Number: 10.1016/j.arcped.2021.09.023
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.647-651
  • Keywords: Hypoxic-ischemic encephalopathy, Therapeutic hypothermia, Calcium, Phosphorus, Magnesium, HYPOMAGNESEMIA
  • Erciyes University Affiliated: Yes


Objectives: Hypocalcemia, hypomagnesemia, and hyperphosphatemia are common electrolyte disturbances in perinatal asphyxia (PA). Different reasons have been proposed for these electrolyte disturbances. This study investigated the effect of the urinary excretion of calcium (Ca), magnesium (Mg), and phosphorus (P) on the serum levels of these substances in babies who were treated using therapeutic hypothermia for hypoxic ischemic encephalopathy (HIE) caused by PA. This study sheds light on the pathophysiology that may cause changes in the serum values of these electrolytes.