A rare but severe complication of filgrastim in a healthy donor: Splenic rupture

AKYOL, GÜLŞAH; Pala, Çiğdem; Yildirim, Afra; Keklika, MUZAFFER; Demir, Koray; Dortdudak, Sümeyra; Sivgin, Serdar; KAYNAR, LEYLAGÜL; Esera, Bulent; ÜNAL, ALİ; Cetin, MUSTAFA

doi:10.1016/j.transci.2013.07.036

A rare but severe complication of filgrastim in a healthy donor: Splenic rupture

AKYOL G., Pala C., Yildirim A., Keklika M., Demir K., Dortdudak S., ...More

TRANSFUSION AND APHERESIS SCIENCE, vol.50, no.1, pp.53-55, 2014 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 50 Issue: 1
Publication Date: 2014
Doi Number: 10.1016/j.transci.2013.07.036
Journal Name: TRANSFUSION AND APHERESIS SCIENCE
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.53-55
Keywords: Splenic rupture, Filgrastim, Stem cell transplantation
Erciyes University Affiliated: Yes

Abstract

Background: Granulocyte-colony stimulating factor (G-CSF) is widely administered to donors who provide peripheral blood stem cells (PBSCs) for individuals who undergo hematopoietic stem cell transplants. G-CSF administration is associated with a small but definite risks of serious adverse events like splenic rupture.