The effects of dimethylsulfoxide in experimental obstructive jaundice

KUCUK C., OK E., YILMAZ Z., SOZUER E. M., Muhtaroglu S., ARAR M.

ACTA CHIRURGICA BELGICA, cilt.103, sa.4, ss.392-395, 2003 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 103 Sayı: 4
  • Basım Tarihi: 2003
  • Doi Numarası: 10.1080/00015458.2003.11679450
  • Dergi Adı: ACTA CHIRURGICA BELGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.392-395
  • Erciyes Üniversitesi Adresli: Evet

Özet

Material and methods : Thirty rats were divided into three groups, as sham, control and DMSO groups. Laparatomy was performed on each animal in the control and DMSO groups and common bile ducts were ligated. Common bile duct was observed but was not ligated for the rats in the sham group. Saline solution injection (1.5 mg/kg/intraperitoneally (ip)) was begun on the first day of surgical procedure and repeated once a day for the next 5 days. The same procedure was performed with DMSO (1.5 mg/kg/ip) instead of saline in the DMSO group. The rats were sacrificed on the postoperative seventh day, at which time venous blood and liver tissue specimens were taken.