The effects of dimethylsulfoxide in experimental obstructive jaundice


KUCUK C., OK E. , YILMAZ Z., SOZUER E. M. , Muhtaroglu S. , ARAR M.

ACTA CHIRURGICA BELGICA, vol.103, no.4, pp.392-395, 2003 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 103 Issue: 4
  • Publication Date: 2003
  • Doi Number: 10.1080/00015458.2003.11679450
  • Title of Journal : ACTA CHIRURGICA BELGICA
  • Page Numbers: pp.392-395

Abstract

Material and methods : Thirty rats were divided into three groups, as sham, control and DMSO groups. Laparatomy was performed on each animal in the control and DMSO groups and common bile ducts were ligated. Common bile duct was observed but was not ligated for the rats in the sham group. Saline solution injection (1.5 mg/kg/intraperitoneally (ip)) was begun on the first day of surgical procedure and repeated once a day for the next 5 days. The same procedure was performed with DMSO (1.5 mg/kg/ip) instead of saline in the DMSO group. The rats were sacrificed on the postoperative seventh day, at which time venous blood and liver tissue specimens were taken.