No improvement of survival with reduced- versus high-intensity conditioning for allogeneic stem cell transplants in Ewing tumor patients

Thiel, U.; Wawer, A.; Wolf, P.; Badoglio, M.; Santucci, A.; Klingebiel, T.; Basu, O.; Borkhardt, A.; Laws, H.; Kodera, Y.; Yoshimi, A.; Peters, C.; Ladenstein, R.; Pession, A.; Prete, A.; Urban, E.; Schwinger, W.; Bordigoni, P.; Salmon, A.; Diaz, M.; Afanasyev, B.; Lisukov, I.; Morozova, E.; Toren, A.; Bielorai, B.; Korsakas, J.; Fagioli, F.; Caselli, D.; Ehninger, G.; Gruhn, B.; Dirksen, U.; Abdel-Rahman, F.; Aglietta, M.; Mastrodicasa, E.; Torrent, M.; Corradini, P.; Demeocq, F.; Dini, G.; Dreger, P.; Eyrich, M.; Gozdzik, J.; Guilhot, F.; Holler, E.; Koscielniak, E.; Messina, C.; Nachbaur, D.; Sabbatini, R.; Oldani, E.; Ottinger, H.; Ozsahin, H.; Schots, R.; Siena, S.; Stein, J.; Sufliarska, S.; ÜNAL, ALİ; Ussowicz, M.; Schneider, P.; Woessmann, W.; Juergens, H.; Bregni, M.; Burdach, S.

doi:10.1093/annonc/mdq703

No improvement of survival with reduced- versus high-intensity conditioning for allogeneic stem cell transplants in Ewing tumor patients

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Thiel U., Wawer A., Wolf P., Badoglio M., Santucci A., Klingebiel T., ...More

ANNALS OF ONCOLOGY, vol.22, no.7, pp.1614-1621, 2011 (SCI-Expanded)

Publication Type: Article / Article
Volume: 22 Issue: 7
Publication Date: 2011
Doi Number: 10.1093/annonc/mdq703
Journal Name: ANNALS OF ONCOLOGY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.1614-1621
Keywords: advanced-stage Ewing tumor, allogeneic stem cell transplantation, graft versus tumor effect, haploidentical stem cell transplantation, reduced, high-intensity conditioning chemotherapy, PERIPHERAL NEUROECTODERMAL TUMORS, TOTAL-BODY IRRADIATION, HIGH-DOSE THERAPY, EUROPEAN INTERGROUP, SARCOMA, BONE, MARROW, GRAFT, TRANSLOCATION, METASTASES
Erciyes University Affiliated: Yes

Abstract

Background: Outcomes of Ewing tumor (ET) patients treated with allogeneic stem cell transplantation (allo-SCT) were compared regarding the use of reduced-intensity conditioning (RIC) and high-intensity conditioning (HIC) regimens as well as human leukocyte antigen (HLA)-matched and HLA-mismatched grafts.