Background and objectives. The most common infectious disease in children is acute upper respiratory tract infection (URTI). Many drugs, especially antitussive drugs, are used for symptomatic treatment. Bee products (propolis, royal jelly, and honey) have antiviral, antibacterial, and antioxidant properties, and they have synergistic effects with antibiotics. The aim of this study was to evaluate the effectiveness of a mixture of bee products in URTI in children.