Microchemical Journal, cilt.217, 2025 (SCI-Expanded, Scopus)
Deep eutectic solvents (DESs) have emerged as critical materials in the development of ecologically friendly microextraction technologies. This umbrella review provides an extensive review of existing review papers to summarize knowledge regarding the development, uses, and future possibilities for DES-based microextraction methods. The selection criteria centered on peer-reviewed systematic and narrative reviews published between 2020 and 2024 that studied DESs in analytical microextraction scenarios. The reviews were categorized into three primary domains: (i) environmental monitoring, (ii) biological and clinical analysis, and (iii) food safety and quality management. Essential subjects include the integration of DES into advanced analytical techniques and their contribution to advancing green chemistry concepts. Recent advancements, including the use of hydrophobic DESs for non-polar analytes, task-specific DESs for selective extractions, and energy-efficient synthesis techniques, were prominently included in the reviewed literature. The next steps include the optimization of natural deep eutectic solvents (NADESs), the development of computational tools for tailored solvent design, and the establishment of circular economy frameworks for the reuse and sustainability of DESs.