In the present study, the methanolic and water extracts of Paronychia mughlaei Chaudhri (Caryophyllaceae) were examined for their total phenolic content, potential antioxidant and antimicrobial activities. The total phenolic contents of the extracts were measured by Folin-Ciocalteu method. Antioxidant activity of both extracts were analysed using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and phosphomolybdenum assay. Both extracts showed antioxidant activity. A correlation between total phenolic content and antioxidant activity was observed. Antimicrobial activities of the both extracts were tested against fifteen microorganisms by agar well diffusion method, at 1, 2.5, 5 and 10% concentrations. The extracts were weakly active against microorganisms tested.