Neurofibromatosis Type 1 with Overlap Turner Syndrome and Klinefelter Syndrome

Hatipoğlu, NİHAL; Kurtoglu, Selim; Kendirci, MUSTAFA; Keskin, Mehmet; Per, HÜSEYİN

doi:10.1093/tropej/fmp053

Neurofibromatosis Type 1 with Overlap Turner Syndrome and Klinefelter Syndrome

Hatipoğlu N., Kurtoglu S., Kendirci M., Keskin M., Per H.

JOURNAL OF TROPICAL PEDIATRICS, cilt.56, sa.1, ss.69-72, 2010 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 56 Sayı: 1
Basım Tarihi: 2010
Doi Numarası: 10.1093/tropej/fmp053
Dergi Adı: JOURNAL OF TROPICAL PEDIATRICS
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.69-72
Anahtar Kelimeler: turner syndrome, klinefelter syndrome, Neurofibromatosis type 1
Erciyes Üniversitesi Adresli: Evet

Özet

Turner's syndrome is a sex chromosome disorder. Klinefelter's syndrome is one of the most severe genetic diseases. Neurofibromatosis is an autosomal dominant disorder characterized by cafe-au-lait spots and fibromatous tumors of the skin. In this article, we report the overlap of neurofibromatosis-1 with Turner and Klinefelter syndromes. Thus, these disorders might overlap within the same patient. Due to these cases, we suggest that each patient with Turner-like symptoms or Klinefelter's-like syndrome, be carefully examined for cafe au lait macules before the initiation of hormone replacement treatment.