Mean Platelet Volume and Its Relation With Arterial Stiffness in Patients With Normotensive Polycystic Kidney Disease


ÖRSÇELİK O. , Kocyigit I. , Akpek M. , DOĞDU O. , Kaya C., ÜNAL A. , ...More

JOURNAL OF INVESTIGATIVE MEDICINE, vol.61, no.3, pp.597-603, 2013 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 61 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.231/jim.0b013e31828218e7
  • Title of Journal : JOURNAL OF INVESTIGATIVE MEDICINE
  • Page Numbers: pp.597-603

Abstract

Background: Autosomal-dominant polycystic kidney disease (ADPKD) demonstrates cardiovascular manifestations, such as hypertension, myocardial infarction, and increased carotid intimae-media thickness. These complications are the main cause of morbidity and mortality in patients with ADPKD. Platelet activation and arterial stiffness are important manifestations that independently predict cardiovascular events. In the present study, we aimed to investigate the relation between arterial stiffness, mean platelet volume (MPV), and highly sensitive C-reactive protein (hs-CRP) in patients with normotensive polycystic kidney disease.