Effects of Organophosphate Poisoning on the Endocrine System in the Long Term: A Pilot Study

Simsek Z. O., Sevim M., Simsek Y., SUNGUR M., GÜNDOĞAN K., Guven M.

ERCIYES MEDICAL JOURNAL, vol.41, no.1, pp.33-36, 2019 (ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 1
  • Publication Date: 2019
  • Doi Number: 10.14744/etd.2019.19122
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.33-36
  • Erciyes University Affiliated: Yes


Objective: Organophosphates (OPs) are widely used for pest control worldwide, leading to increased risk for human exposure. The acute hormonal effects of OP include deficiencies in the thyroid-stimulating hormone (TSH), adrenocorticotropic hormone, and insulin-like growth factor 1 hormone correlated with the levels of cholinesterase. Most patients with OP-related hormone deficiency recover at 3 months of follow-up. However, the chronic effects of these chemicals are not clear. The aim of the present study was to determine the chronic influences of OP on pituitary functions in patients who had OP poisoning.