Increased plasma soluble human leukocyte antigen-G in persistent wheezy infants


TAHAN F. , GUNGOR H. E. , Akar H. H. , SARAYMEN B.

PEDIATRICS INTERNATIONAL, cilt.59, sa.5, ss.530-533, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 59 Konu: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1111/ped.13207
  • Dergi Adı: PEDIATRICS INTERNATIONAL
  • Sayfa Sayıları: ss.530-533

Özet

Background: Human leukocyte antigen (HLA)-G is a non-classical major histocompatibility complex class I antigen characterized by limited polymorphism in its coding region, unique tissue expression pattern in physiologic conditions and immunomodulatory properties. Recently, the level of soluble (s) HLA-G was found to be higher in atopic asthma and allergic rhinitis, but this remains to be clarified in wheezy infants. The aim of the present study was therefore to investigate sHLA-G in wheezy infants.