Increased plasma soluble human leukocyte antigen-G in persistent wheezy infants

TAHAN F., GUNGOR H. E., Akar H. H., SARAYMEN B.

PEDIATRICS INTERNATIONAL, cilt.59, sa.5, ss.530-533, 2017 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 59 Sayı: 5
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1111/ped.13207
  • Dergi Adı: PEDIATRICS INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.530-533
  • Anahtar Kelimeler: asthma, children, persistent wheeze, soluble human leukocyte antigen G, HLA-A,-B,-C SERUM-LEVELS, HLA-G, ALLERGIC RHINITIS, YOUNG-CHILDREN, SUBLINGUAL IMMUNOTHERAPY, CLASS-I, ASTHMA, RISK, TROPHOBLAST, PHENOTYPES
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background: Human leukocyte antigen (HLA)-G is a non-classical major histocompatibility complex class I antigen characterized by limited polymorphism in its coding region, unique tissue expression pattern in physiologic conditions and immunomodulatory properties. Recently, the level of soluble (s) HLA-G was found to be higher in atopic asthma and allergic rhinitis, but this remains to be clarified in wheezy infants. The aim of the present study was therefore to investigate sHLA-G in wheezy infants.