Surgery is the primary treatment of aortic coarctation in all newborns, including low birth weight premature infants. Balloon angioplasty procedure in the treatment of native coarctation of the newborn is controversial due to high rates of restenosis and complications such as increased risk of aneurysm formation and damage to the peripheral artery involved in the intervention. Balloon angioplasty is often performed as a palliative treatment particularly in newborns with impaired cardiac functions indicating high rates of mortality. We believe that this procedure may be performed as a palliative treatment for low birth weight infants in centers lacking adequate surgical experience. Herein, we define a successful balloon angioplasty procedure which we carried out using the femoral artery route in a low birth weight premature infant with coarctation of the aorta.