Cohen syndrome with acanthosis nigricans and insulin resistance


KUMANDAS S., GUMUS H., KURTOGLU S. , ELMAS B. , Kontas O.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.14, ss.807-810, 2001 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 14 Konu: 6
  • Basım Tarihi: 2001
  • Doi Numarası: 10.1515/jpem.2001.14.6.807
  • Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
  • Sayfa Sayıları: ss.807-810

Özet

Cohen syndrome is a rare genetic disorder consisting of truncal obesity, hypotonia, mental retardation, microcephalia, characteristic facial appearance and ocular anomalies. Other diagnostic clinical features include narrow hands and feet, low growth parameters, neutropenia and chorioretinal dystrophy, Acanthosis nigricans is a cutaneous disorder characterized by hyperpigmentation and papillomatosis. Syndromal acanthosis nigricans may occasionally appear as a feature of several specific syndromes. We report a patient showing the typical characteristics of Cohen syndrome with acanthosis nigricans and hyperinsulinemia.