Cohen syndrome with acanthosis nigricans and insulin resistance

KUMANDAS, S; GUMUS, H; KURTOGLU, Selim; ELMAS, Bahri; Kontas, OLGUN

doi:10.1515/jpem.2001.14.6.807

Cohen syndrome with acanthosis nigricans and insulin resistance

Atıf İçin Kopyala

KUMANDAS S., GUMUS H., KURTOGLU S., ELMAS B., Kontas O.

JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM, cilt.14, sa.6, ss.807-810, 2001 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 14 Sayı: 6
Basım Tarihi: 2001
Doi Numarası: 10.1515/jpem.2001.14.6.807
Dergi Adı: JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.807-810
Erciyes Üniversitesi Adresli: Evet

Özet

Cohen syndrome is a rare genetic disorder consisting of truncal obesity, hypotonia, mental retardation, microcephalia, characteristic facial appearance and ocular anomalies. Other diagnostic clinical features include narrow hands and feet, low growth parameters, neutropenia and chorioretinal dystrophy, Acanthosis nigricans is a cutaneous disorder characterized by hyperpigmentation and papillomatosis. Syndromal acanthosis nigricans may occasionally appear as a feature of several specific syndromes. We report a patient showing the typical characteristics of Cohen syndrome with acanthosis nigricans and hyperinsulinemia.