Finasteride treatment for one year in 35 hirsute patients

Bayram F., Muderris I. I., Sahin Y., Kelestimur F.

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, vol.107, no.3, pp.195-197, 1999 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 107 Issue: 3
  • Publication Date: 1999
  • Doi Number: 10.1055/s-0029-1212097
  • Journal Name: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.195-197
  • Keywords: finasteride, hirsutism, 5-ALPHA-REDUCTASE INHIBITOR FINASTERIDE, IDIOPATHIC HIRSUTISM, WOMEN, SPIRONOLACTONE, FLUTAMIDE
  • Erciyes University Affiliated: Yes

Abstract

This study was performed to confirm the favourable therapeutic effects of finasteride in hirsute women as described by previous publications of different research groups. Our study was a non-randomized, prospective clinical trial. Thirty five patients with hirsutism were included in the study. The patients received 5 mg finasteride orally once per day over a period of 12 months. Hirsutism score, FSH, LH, E-2, total T, free T, androstenedione (A), DHEAS, 17-hydroxyprogesterone (17-OHP) and sex hormone-binding globulin (SHBG) levels were determined in all the patients before treatment and every 6 months during treatment.