Relationship Between C-Reactive Protein to Albumin Ratio and Coronary Collateral Circulation in Patients With Stable Coronary Artery Disease

Kelesoglu Ş., Yilmaz Y., Elcık D.

Angiology, cilt.72, sa.9, ss.829-835, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 72 Sayı: 9
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1177/00033197211004392
  • Dergi Adı: Angiology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, CINAHL, EMBASE, Food Science & Technology Abstracts, MEDLINE
  • Sayfa Sayıları: ss.829-835
  • Anahtar Kelimeler: C-reactive protein to albumin ratio, coronary collateral circulation, stable coronary artery disease, Rentrop grade
  • Erciyes Üniversitesi Adresli: Evet

Özet

© The Author(s) 2021.We investigated the relationship between the C-reactive protein (CRP) to albumin ratio (CAR) and coronary collateral circulation (CCC) in stable coronary artery disease (CAD). Patients with stable CAD (n = 354) who underwent coronary angiography for suspected CAD and had a total occlusion ≥1 major coronary artery were included in the study. The participants were divided into 2 groups according to the Rentrop score as satisfactory CCC (Rentrop 2-3) and poor CCC (Rentrop 0-1). Patients who had poor CCC had a higher CRP, neutrophil/lymphocyte ratio (NLR), and CAR levels compared with those who had satisfactory CCC (P <.001, P =.046, P <.001, respectively). The CAR (odds ratio: 3.522, 95% CI: 2.515-4.932, P <.001), CRP, NLR, and diabetes mellitus were independent predictors of poor CCC. In receiver operator characteristic curve (ROC) analysis, the optimal cutoff value of CAR to predict poor CCC was 1.27 (area under ROC curve = 0.735 [95% CI: 0.667-0.803], P <.001). A raised CAR may be an independent predictor of poor CCC.