The effect of volume replacement during therapeutic leukapheresis on white blood cell reduction in patients with extreme leukocytosis

Kurnaz F., Sivgin S., Pala C., yildirim R., Baldane S., Kaynar L., ...Daha Fazla

TRANSFUSION, cilt.53, sa.11, ss.2629-2634, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 11
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1111/trf.12141
  • Dergi Adı: TRANSFUSION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.2629-2634
  • Erciyes Üniversitesi Adresli: Evet

Özet

BackgroundExtreme leukocytosis, generally defined as a white blood cell (WBC) count of more than 100x10(9)/L consisting largely of blast cells, especially when accompanied by clinical signs and symptoms of leukostasis or hyperviscosity, often predicts a poor clinical outcome in patients with acute leukemia. In this study, we aimed to investigate the effect of volume replacement (VR) during therapeutic leukapheresis (TA) procedure on early mortality rate and WBC reduction.