A comparison between low-dose (1 mu g), standard-dose (250 mu g) ACTH stimulation tests and insulin tolerance test in the evaluation of hypothalamo-pituitary-adrenal axis in primary fibromyalgia syndrome

Kirnap, MEHMET; Çolak, Ramis; Eser, Cengiz; Ozsoy, O; Tutus, AHMET; Kelestimur, F

doi:10.1046/j.1365-2265.2001.01373.x

A comparison between low-dose (1 mu g), standard-dose (250 mu g) ACTH stimulation tests and insulin tolerance test in the evaluation of hypothalamo-pituitary-adrenal axis in primary fibromyalgia syndrome

Kirnap M., Çolak R., Eser C., Ozsoy O., Tutus A., Kelestimur F.

CLINICAL ENDOCRINOLOGY, cilt.55, sa.4, ss.455-459, 2001 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 55 Sayı: 4
Basım Tarihi: 2001
Doi Numarası: 10.1046/j.1365-2265.2001.01373.x
Dergi Adı: CLINICAL ENDOCRINOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.455-459
Erciyes Üniversitesi Adresli: Hayır

Özet

Objective: Primary fibromyalgia syndrome (PFS) is a nonarticular rheumatological syndrome characterized by disturbances in the hypothalamo-pituitary-adrenal (HPA) axis. The site of the defect in the HPA axis is a matter of debate. Our aim was to evaluate the HPA axis by the insulin-tolerance test (ITT), standard dose (250 mug) ACTH test (SDT) and low dose (1 mug) ACTH test (LDT) in patients with PFS.