Lack of serum antineuronal antibodies in children with autism

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BAYRAM A., KARDAŞ F., DEMİRCİ E., GÖKAHMETOĞLU S., ÖZMEN S., CANPOLAT M., ...Daha Fazla

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.117, sa.2, ss.77-79, 2016 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 117 Sayı: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4149/bll_2016_015
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.77-79
  • Anahtar Kelimeler: Autism, antineuronal antibodies, glutamic acid decarboxylase, glutamate receptor, ganglioside antibodies, autoimmunity, SPECTRUM DISORDERS, DISEASE, GANGLIOSIDES, ASSOCIATION, SEVERITY, FAMILY
  • Erciyes Üniversitesi Adresli: Evet

Özet

OBJECTIVE: Autism spectrum disorders (ASDs) are a severe group of neurodevelopmental disorders that are characterized by impairment in social communication, and imagination and social interaction. The aetiology of autism is complex, but some studies suggest autoimmunity to the central nervous system in the pathogenesis. The aim of this study is to investigate the positivity of antineuronal antibodies including anti-glutamic acid decarboxylase antibodies (anti-GAD), anti-glutamate receptor (anti-GIuR) antibodies and seven types of anti-ganglioside antibodies, in children with autism.