Lack of serum antineuronal antibodies in children with autism


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BAYRAM A., KARDAŞ F. , DEMİRCİ E. , GÖKAHMETOĞLU S. , ÖZMEN S. , CANPOLAT M. , ...More

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, vol.117, no.2, pp.77-79, 2016 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Volume: 117 Issue: 2
  • Publication Date: 2016
  • Doi Number: 10.4149/bll_2016_015
  • Title of Journal : BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Page Numbers: pp.77-79
  • Keywords: Autism, antineuronal antibodies, glutamic acid decarboxylase, glutamate receptor, ganglioside antibodies, autoimmunity, SPECTRUM DISORDERS, DISEASE, GANGLIOSIDES, ASSOCIATION, SEVERITY, FAMILY

Abstract

OBJECTIVE: Autism spectrum disorders (ASDs) are a severe group of neurodevelopmental disorders that are characterized by impairment in social communication, and imagination and social interaction. The aetiology of autism is complex, but some studies suggest autoimmunity to the central nervous system in the pathogenesis. The aim of this study is to investigate the positivity of antineuronal antibodies including anti-glutamic acid decarboxylase antibodies (anti-GAD), anti-glutamate receptor (anti-GIuR) antibodies and seven types of anti-ganglioside antibodies, in children with autism.