Lack of serum antineuronal antibodies in children with autism


BAYRAM A. , KARDAŞ F. , DEMİRCİ E. , GÖKAHMETOĞLU S. , ÖZMEN S. , CANPOLAT M. , et al.

BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, cilt.117, ss.77-79, 2016

  • Cilt numarası: 117 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4149/bll_2016_015
  • Dergi Adı: BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY
  • Sayfa Sayısı: ss.77-79

Özet

OBJECTIVE: Autism spectrum disorders (ASDs) are a severe group of neurodevelopmental disorders that are characterized by impairment in social communication, and imagination and social interaction. The aetiology of autism is complex, but some studies suggest autoimmunity to the central nervous system in the pathogenesis. The aim of this study is to investigate the positivity of antineuronal antibodies including anti-glutamic acid decarboxylase antibodies (anti-GAD), anti-glutamate receptor (anti-GIuR) antibodies and seven types of anti-ganglioside antibodies, in children with autism.