Hepatoprotective effect of ghrelin on carbon tetrachloride-induced acute liver injury in rats

ÇETİN E., KANBUR M., Cetin N., ERASLAN G., ATASEVER A.

REGULATORY PEPTIDES, cilt.171, ss.1-5, 2011 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 171
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1016/j.regpep.2011.05.010
  • Dergi Adı: REGULATORY PEPTIDES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.1-5
  • Anahtar Kelimeler: Ghrelin, Antioxidant effect, Hepatoprotective effect, Acute liver injury, ANTIOXIDANT ENZYME-ACTIVITY, ACTIVE OXYGEN-METABOLISM, ENDOGENOUS NITRIC-OXIDE, LIPID-PEROXIDATION, OXIDATIVE STRESS, HEME OXYGENASE-1, ENDOTOXIC-SHOCK, SUPEROXIDE, PEROXYNITRITE, MECHANISMS
  • Erciyes Üniversitesi Adresli: Evet

Özet

Background & Aims: Recent studies have revealed that ghrelin may be an antioxidant and antiinflammatory agent. Oxidative stress are considered to play a prominent causative role in the development of various hepatic disorders. We investigated whether ghrelin plays a protective role against carbon tetrachloride (CCl(4))-induced acute liver injury in rats.