(Substituted Ylidene)Amino-2-Oxo-Indolylidene Thioureas and Bis(2-Oxo-Indolylidene)Urea from (Ylidene)Thiocarbonohydrazides and Isatylidene Malononitrile


Hassan A. A., Mohamed S. K., Abdel-Latif F. F., Mostafa S. M., Abdel-Aziz M., Mague J. T., ...More

JOURNAL OF HETEROCYCLIC CHEMISTRY, vol.54, no.2, pp.959-964, 2017 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 54 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.1002/jhet.2660
  • Journal Name: JOURNAL OF HETEROCYCLIC CHEMISTRY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.959-964
  • Erciyes University Affiliated: Yes

Abstract

A simple and efficient synthesis of (substituted ylidene)(2-oxoindolylidene)thiocarbohydrazones and bis(2-oxoindolylidene)urea was achieved by the reaction of (substituted ylidene)thiocarbonohydrazides with isatylidene malononitrile. Rational for this conversation involving the nucleophilic additions on the dicyanomethylene carbon atom is presented. The structures of the products have been confirmed by using spectral and single-crystal X-ray analyses.