Ni-Co MOF/ Zn-NTA nanoflowers as adsorbent for dispersive solid phase microextraction of triazole fungicides in water and fruit juice samples before their HPLC-DAD detection

ÖZALP Ö., SOYLAK M.

Journal of Food Composition and Analysis, vol.141, 2025 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 141
  • Publication Date: 2025
  • Doi Number: 10.1016/j.jfca.2025.107349
  • Journal Name: Journal of Food Composition and Analysis
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Analytical Abstracts, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Food Science & Technology Abstracts, Veterinary Science Database
  • Keywords: Dispersive solid phase microextraction, Ni-Co MOF/Zn-NTA, Fruit juice, Water samples, HPLC-DAD, Triazole fungicides
  • Erciyes University Affiliated: Yes

Abstract

A dispersive solid phase microextraction (d-SPME) method was developed for the trace level analysis of Difenoconazole (DFC), Hexaconazole (HXC) and Triticonazole (TRT), which are the triazole fungicides most commonly used by vegetable and fruit producers. Ni-Co MOF/Zn-NTA nanoparticles synthesized for precise and precise extraction of three different triazole fungicides without matrix interference before developing the method were successfully characterized by FT-IR, XRD, FE-SEM, SEM-EDX. pH (5), amount of adsorbent (20 mg), adsorption time (6 min) and desorption time (6 min), sample volume (30 mL) and type of eluent (methanol/ammonia mixture (95/5, v/v) were optimized. Enrichment of three different triazole fungicides were done under optimal conditions for real samples. The preconcentration factor was 30. The results of LOD and LOQ values for DFC, HXC and TRT were determined as 1.5–2.5 ng mL−1 and 5.3–8.0 ng mL−1, respectively. In the developed d-SPME method, RSD values were determined to be below 5 %.